"Yes, they are quite advanced. They have abducted everyone here, no one, as far as I know, remembers being taken, anyone with enhanced abilities has been weakened, and each morning we suddenly appear in our beds," Wesker had absolutely know idea what they were doing, to be able to maintain such a level of effectiveness. Then again, patients did vanish entirely on occasion. Perhaps they became resistant to whatever methods were being used and had to be removed?